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Nailing his theses to the door of the castle church in Wittenberg came like a thunderclap.  It changed the church and society. The unity of church and state, that had prevailed up until then, was broken and they instead became opposing parties. Individual persons and preachers were given the right to speak out publicly with a conscience oriented towards the bible and reason. 

Since the European powers had begun to divide the world up among themselves at this time, the religious division also continued in many colonies. The Protestantism began to spread out in North America, where many of the reform-minded dissenters emigrated to, in order to practice their beliefs freely. The ideas of the Enlightenment fit the requests of the Baptists, the Quakers and the Free Spiritualists that had an effect on the formation of religious freedom and the development of the human rights. So what had started in Wittenberg didn't only change Germany, but had an impact on Europe and the entire world.